We have developed proprietary synthesis methods for next generation 2D semiconductor and quantum materials with significant broad electronics upgrade implications.
We are leveraging these materials into semiconductor based biosensing systems with unique surface chemistry enabling a foundational shift in sensing.
Our platform enables continuous multi biomarker sensing beyond glucose using sweat, with future expansion into additional biofluids and microneedle systems.
Competing biosensing platforms require years and tens of millions of dollars to develop each new single biomarker capability. We already have 14+ lab validated biomarkers with a pathway toward a library of 100+ biomarkers within the same core platform architecture.
From glucose to 100 plus biomarkers unlocking continuous biological intelligence. Nano Performance Technologies has developed a 2D semiconductor sensing architecture validated through human and equine laboratory and field trials with outstanding results, designed to scale across biomarkers, products, and licensing markets without requiring redesign of the underlying platform. Initial product: a lab validated neuro hormonal wearable capable of detecting dopamine, norepinephrine, and cortisol in sweat, enabling real time human performance and wellness monitoring without FDA dependency. Demonstrated signal parity with gold standard HPLC laboratory methods without the laboratory infrastructure.
NPT is not building a single wearable product.
It is building the sensing architecture beneath a new generation of molecular devices.
Each validated biomarker expands the platform’s licensing surface area, product optionality, and future data value without requiring a new sensing system.
The current biosensing market is constrained by architectures that only detect one biomarker at a time. Every expansion requires rebuilding the system limiting speed, scalability, and economic viability.
Existing biosensor companies are constrained to single target sensing systems like glucose monitors that must be entirely rebuilt for each new biological target. Expanding has historically required multi year development cycles and capital intensive redesigns costing tens of millions each. There is no path to platform scale from these architectures and have been highly capital inefficient.
NPT's 2D semiconductor platform supports 14 validated biomarkers today and the library expands without requiring device level redesign. Each new biomarker adds to the same foundation. The same architecture that detects neurotransmitters in sweat today will power clinical grade microneedle devices, licensing deals, and AI data infrastructure tomorrow. NPT's semiconductor materials introduce unique surface chemistry, enabling biological signal transduction with levels of sensitivity and reliability not achievable through conventional sensing approaches.
Continuous glucose monitoring validated the behavior. The next phase is not another single analyte it is real time access to multiple biological systems through a single sensing architecture.
NPT’s 2D semiconductor platform directly transduces molecular signals into electrical output, enabling single, dual, and multi analyte detection without redesigning the underlying system.
Dopamine and norepinephrine enable real time insight into focus, cognitive load, and acute stress response. Dual marker detection has already been demonstrated in human testing.
Cortisol enables continuous tracking of chronic stress, recovery cycles, and physiological baseline shifts completing the initial neuro-hormonal panel.
Glucose, lactate, and uric acid support real time tracking of energy utilization, exertion, and physiological load across performance environments.
Future panels include estradiol and testosterone, expanding into endocrine health, performance optimization, and clinical monitoring applications.
Cytokines (IL-6, TNF-alpha) and immune signaling markers enable continuous tracking of inflammation, disease progression, and therapeutic response.
Creatinine, electrolytes, and detectable drug compounds enable continuous monitoring of organ function, metabolism, and dosing dynamics.
Each biomarker can be deployed individually, in dual marker configurations, or as expanding panels with increasing data density, product capability, and licensing value at each step.
Applications span human performance, clinical devices, defense and space, and animal health including equine performance validated across both human and horse studies.
Validated in early human testing with real time multi biomarker detection outside controlled lab environments. TellU Sense is the first commercial expression of the platform an initial non invasive wedge into continuous molecular sensing, not the limit of the platform.
Each new biomarker is deployed onto the same semiconductor platform. Devices are configured for specific use cases while the underlying library continues to expand and compound.
The first product is a lab-validated neuro-hormonal wearable a non invasive, sweat based system designed for human performance. It enables real time monitoring of dopamine, norepinephrine, and cortisol, providing insight into focus, acute stress, and chronic stress without requiring FDA approval for initial market entry.
This serves as the initial commercial wedge demonstrating multi biomarker capability in a real world product while the platform scales through larger licensing partnerships across wearables, diagnostics, and biosensing companies.
This is a platform system. Each layer reinforces the others expanding licensing surface area, product optionality, and long term data infrastructure.
Biomarker capabilities and platform access licensed to wearables, diagnostics, and biosensor companies. Structured deals target the $50M–$500M range as the library expands.
PrimaryTellU Sense wearable systems sweat based market entry (non-FDA) with FDA microneedle optionality extending into clinical grade devices.
Near-termReal time biological validation for pharmaceuticals and nutraceuticals. Positioned to become a new industry standard for efficacy measurement.
EmergingLive human biological data at scale high value datasets for AI models that cannot rely on synthetic data. A new category of data asset.
Long-term
Technology validated through funded research, lab testing, and early human trials.
Demonstrated multi neurotransmitter detection in human subjects a milestone no competitor has reached with a scalable architecture. Live stress and focus neurotransmitter markers are now detectable through sweat with a growing validated biomarker library.
Lab validated across a growing biomarker library, each supported by the same underlying semiconductor architecture.
The underlying technology portfolio has been supported through programs associated with the United States Department of Defense, United States Air Force, United States Department of Energy, and the National Science Foundation, alongside research validation engagement with many leading Universities.
Active discussions with multiple large corporate development and venture groups across semiconductor and medtech, including interest in leading a future Series A.
Interviews across consumers, medtech diagnostics and research organizations confirmed strong pent up demand for multi analyte sensing for consumers and validated licensing as the preferred commercialization pathway.
Biosensing has been constrained by iteration speed and cost. Legacy systems require years and significant capital to add a single biomarker, limiting scalability, data depth, and commercial potential. NPT enters with a platform that removes both constraints.
The bottleneck in biosensing is not detection. It is iteration speed and cost.
| Key Constraint | Legacy Systems | NPT Platform |
|---|---|---|
| Time to add new biomarker | Years + high cost | Weeks |
Competitors are structurally limited to narrow biomarker sets and cannot economically expand into large libraries or support broad licensing strategies. NPT’s platform uniquely enables both single and multi marker licensing across expanding biomarkers library.
| Company | Architecture | Biomarkers | Scalable Platform | Semiconductor IP | Revenue Status | Capital Raised |
|---|---|---|---|---|---|---|
| NPT (us) | 2D Semiconductor | 14 validated | ✓ | ✓ | Pre-revenue | $1.5M (raising) |
| Typical Biosensor Co. | Biorecognition-limited | 1–3 | , | , | Pre-revenue | $10M–$100M+ |
| Wearable Biosensor Co. | Single-analyte | 1 | , | , | Pre-revenue | $50M–$300M+ |
| Diagnostics Platform | Enzyme-coupled electrochemical | 3–5 | Partial | , | Early revenue | $30M–$150M+ |
This round funds execution, not discovery. Investors are entering at the earliest commercialization inflection before revenue visibility, before licensing scale, before product launch.
This round represents a late seed bridge into commercialization ahead of licensing conversion, product deployment, and revenue visibility. Execution from this stage is expected to materially re rate the company as it transitions into commercialization and licensing scale.
This round is designed to unlock a significant re-pricing event, positioning the company for a Series A in the $75M–$300M range.
Investors are entering before: revenue visibility licensing scale product launch. This is one of the last entry points before commercial launch and the associated valuation re-pricing.
Already in discussions with multiple corporate VC and corporate development groups across semiconductor and medtech. Active dialogue with investment banks and SPAC sponsors as part of a long-term capital markets strategy.
Be clear-eyed about what this is and what it isn't.
You are a patient, thesis driven investor comfortable with pre revenue deep tech. You understand platform value, IP moats, and the upside of entering before commercial scale. You want to be in before the repricing.
If you require current revenue, proven commercial scale, or near term liquidity, this is not the right opportunity. We are pre revenue and early in commercialization. The upside is real but it requires conviction at this stage.
This is not an abstract research effort. NPT combines Purdue grade technical depth with capital markets and strategic execution expertise.
Capital markets and deep tech commercialization background, with experience in deal origination, partnerships, and strategic execution in advanced technologies.
Multi award winning Purdue based expertise in biosensing, 2D materials, and semiconductor systems. Directly responsible for the $4M+ in federal non dilutive funding and the 14-biomarker validated platform.
PhD-level biosensor scientist with direct experience advancing continuous monitoring systems through clinical development and regulatory pathways, including major contributions to widely deployed large commercial biosensor platforms.
We are in active discussions with select investors. If you believe 2D semiconductor based biosensing is a generational platform opportunity, we'd welcome a conversation.